Wednesday, August 14, 2013

What Else can be Done for Chronic Dry Eye Besides Medication?

Research that has been published in the July issue of Cornea, suggests that essential fatty acids may be of benefit for those who suffer from chronic dry eyes.  I know that one of my patient's back some years ago suffered from this and it truly affected her quality of life.

Gamma linolenic acid (GLA) and Omega 3 fatty acids were the two specific fats chosen.  Foods such as fatty fish, nuts, hemp hearts and organic oils are all high in essential fatty acids and should be eaten, frequently.  In this study, the research team followed 38 post-menopausal women who were suffering from tear production dysfunction.  As this was a randomized trial, the subjects were assigned either to the fatty acid supplementation group or the placebo group for six months.  The women's progress was measured at 4, 12 and 24 weeks, respectively and the Ocular Surface Disease Index score was used to detect any changes.  The results showed a marked, statistically significant improvement in this Index score by the group taking the fatty acid supplement over the placebo group.  The women on the supplement reported an improvement in eye irritation, but did not see a significant improvement in tear production.  

The authors admit to needing additional research about the efficacy of essential fatty acid supplementation in tear production, but I believe that they might do well with using organic food sources of these and other essential fatty acids rather than a lab-produced supplement. That suggestion aside, I think it's really worth looking at what mechanisms are imbalanced to cause this problem in the first place.  Eating a diet high in phytonutrients, low in animal protein and balanced in acid/alkaline ratio will go a long way to preventing many of today's stress and inflammation-induced maladies.

Sheppard JD Jr, Singh R, McClellan AJ, et al. Long-term Supplementation With n-6 and n-3 PUFAs Improves Moderate-to-Severe Keratoconjunctivitis Sicca: A Randomized Double-Blind Clinical Trial. Cornea. 2013 Jul 23.

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